🌟 Top Tranexamic Acid Topicals for Skin Brightening
(Medicinal Products & Functional Cosmetics Included)
Are you struggling with melasma, dark spots, or uneven skin tone?
Tranexamic acid has emerged as one of the most trusted ingredients for pigmentation treatment — both in prescription medications and cosmeceutical skincare.
Here’s a curated list of the best tranexamic acid-based topical products, from dermatologist-prescribed formulas to gentle daily brightening creams.
🔹 Medicinal or Quasi-Drug Grade Topical Products
| Product Name | Manufacturer | TXA % | Key Ingredients | Targeted Concerns | Country | Rx Required |
|---|---|---|---|---|---|---|
| Transino Whitening Essence EX(トランシーノ薬用ホワイトニングエッセンスEX) | Daiichi Sankyo Healthcare | ~2% | Tranexamic Acid, Licorice Extract, Vitamin Derivatives | Melasma, freckles, UV-induced spots | 🇯🇵 Japan | ❌ (Quasi-drug) |
| Dominas Cream 5.0 | Taegeuk Pharm | ~4–5% (estimated) | Tranexamic Acid, AA2G (Vitamin C), botanical extracts | Deep pigmentation, age spots, melasma | 🇰🇷 Korea | ❌ (Functional cosmetic) |
| Tranacix Depigmenting Cream | LSI (France) | 3% | Tranexamic Acid, SPF filters, plant-based complex | Melasma, post-inflammatory pigmentation | 🇹🇼 Taiwan / 🇫🇷 France | ❌ |
| Belo Intensive Whitening Cream | Belo (Philippines) | Not stated | Tranexamic Acid, Kojic Acid, SPF30 | Acne marks, sun damage, melasma | 🇵🇭 Philippines | ❌ |
| Mesoestetic Melan Tran3x Gel Cream | Mesoestetic Pharma Group | 3% | Tranexamic Acid, Niacinamide, Enzymacid™ complex | PIH, melasma, uneven tone | 🇪🇸 Spain | ❌ (Clinic distribution) |
🔹 Prescription-Based Medicinal Topicals
| Product Name | Manufacturer | TXA % | Use | Country | Rx Required |
|---|---|---|---|---|---|
| Generic TXA topical cream (various) | Korean pharma companies | 5–10% | Post-laser PIH, melasma treatment | 🇰🇷 South Korea | ✅ |
| Compounded TXA creams (custom) | Pharmacy compounded | Variable | Custom melasma/pigmentation treatment | 🇺🇸 USA, 🇯🇵 Japan, 🇨🇳 China | ✅ |
| Clinic TXA formulas | In-house or pharma | 5%+ | Often paired with other actives (Vit C, steroids) | 🇨🇳 China, 🇯🇵 Japan | ✅ |
🔹 Global Functional Cosmetics with Brightening Claims
| Product Name | Brand | TXA % | Key Features | Country |
|---|---|---|---|---|
| SkinCeuticals Discoloration Defense | SkinCeuticals (L’Oréal) | 3% | TXA, Niacinamide, Kojic Acid, HEPES | 🇺🇸 USA, 🌍 Global |
| Murad Rapid Dark Spot Correcting Serum | Murad | Not stated | TXA, Ethyl Resorcinol, Glycolic Acid, Niacinamide | 🇺🇸 |
| The INKEY List Tranexamic Acid Night Treatment | The Inkey List | 2% | TXA, Acai Extract, Vitamin C derivative | 🇬🇧 UK, 🌍 Global |
✅ How to Choose the Right Tranexamic Acid Product
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For severe melasma or fast results → Go with prescription topical formulations (5–10%)
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Post-laser pigmentation or spot prevention → Try quasi-drugs or dermatologist-formulated creams
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For daily care and maintenance → Choose 2–3% TXA-based cosmetics
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Need extra power? → Look for products combining TXA + Vitamin C or Niacinamide
